Hardy I R, Dittmann S, Sutter R W
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Lancet. 1996 Jun 22;347(9017):1739-44. doi: 10.1016/s0140-6736(96)90811-9.
Since 1990, an epidemic of diphtheria has spread throughout the newly independent states of the former Soviet Union, and by 1995 a total of 47 808 cases were reported. During the early stages of the epidemic, adequate control measures were not taken and vaccine was in short supply; possible contributing factors to the spread of the epidemic are the presence of highly susceptible child and adult populations, socioeconomic instability, population movement, and a deteriorating health infrastructure. Although WHO views the epidemic as an International public-health emergency and, together with UNICEF and the International Red Cross, has formulated a strategy to combat the epidemic, the necessary funds have not been made fully available. Current vaccination recommendations also need to be reviewed to ensure that population immunity will be adequate to prevent any resurgence of diphtheria in Europe and North America.
自1990年以来,白喉疫情在前苏联的新独立国家蔓延,到1995年共报告了47808例病例。在疫情初期,未采取充分的控制措施且疫苗供应短缺;疫情蔓延的可能促成因素包括存在高度易感的儿童和成人人群、社会经济不稳定、人口流动以及日益恶化的卫生基础设施。尽管世卫组织将该疫情视为国际公共卫生紧急情况,并与联合国儿童基金会和国际红十字会共同制定了抗击疫情的战略,但所需资金尚未完全到位。当前的疫苗接种建议也需要重新审视,以确保人群免疫力足以预防欧洲和北美的白喉再次流行。