Picramenos D, Deliveliotis C, Alexopoulou K, Makrichoritis C, Kostakopoulos A, Dimopoulos C
Department of Urology, Sismanoglion Hospital, Athens, Greece.
Urol Int. 1996;56(2):86-9. doi: 10.1159/000282817.
The aim of our study is to determine the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) as a method of treatment of nephrolithiasis in childhood. Between 1986 and 1994, 50 children with renal calculi were treated by ESWL in our department. The age of the children ranged from 8 months to 14 years. Thirty-three of them were boys and 17 girls. The stone location was in the renal pelvis in 38 cases, in the upper renal calyx in 4 cases, in the lower calyx in 2, while 6 children had staghorn calculi. The stone size ranged between 3 and 39 mm. All treatments were performed with Dornier HM4 except 12 children, all older than 10 years, who underwent ESWL with Dornier HM3. All ESWL procedures took place under general anesthesia or sedation with ketamine. The number of shock waves varied between 400 and 2,000 per treatment and the standard maximum generator voltage was 18 kV. The overall stone clearance rate at 1 month was 66%. Fourteen children with large residual fragments underwent a second ESWL procedure 3 months later. With a mean follow-up of 33 months, 41 children (82%) are stone-free. Ten children developed urinary tract infection and 5 Steinstrasse. Twelve children had a pre- and post-ESWL DMSA scan and no permanent impairment of renal function was observed. We conclude that ESWL is the treatment of choice for urinary tract lithiasis in childhood. It is a low-risk method, without serious complications, which yields as high a success rate in children as in adults. We believe that as the stone fragmentation and clearance is much higher in children that in adults, the method must be the initial approach and may be the monotherapy even in staghorn or complex stones.
我们研究的目的是确定体外冲击波碎石术(ESWL)作为治疗儿童肾结石方法的有效性和安全性。1986年至1994年间,我科对50例肾结石患儿进行了ESWL治疗。患儿年龄从8个月至14岁。其中33例为男孩,17例为女孩。结石位于肾盂38例,上肾盏4例,下肾盏2例,6例为鹿角形结石。结石大小在3至39毫米之间。除12例年龄超过10岁的患儿使用多尼尔HM3进行ESWL外,所有治疗均采用多尼尔HM4进行。所有ESWL手术均在全身麻醉或氯胺酮镇静下进行。每次治疗的冲击波次数在400至2000次之间,标准最大发生器电压为18 kV。1个月时的总体结石清除率为66%。14例有大量残留碎片的患儿在3个月后接受了第二次ESWL手术。平均随访33个月,41例患儿(82%)无结石。10例患儿发生尿路感染,5例出现石街。12例患儿在ESWL前后进行了二巯基丁二酸(DMSA)扫描,未观察到肾功能的永久性损害。我们得出结论,ESWL是儿童尿路结石的首选治疗方法。它是一种低风险方法,无严重并发症,在儿童中的成功率与成人一样高。我们认为,由于儿童的结石破碎和清除率比成人高得多,该方法必须作为初始方法,甚至在鹿角形或复杂结石的治疗中也可能作为单一疗法。