使用一种简单的可回收装置封堵新生儿动脉导管未闭：一项可行性研究。

Occlusion of the neonatal patent ductus arteriosus with a simple retrievable device: a feasibility study.

作者信息

Neuss M B, Coe J Y, Tio F, Le T P, Grabitz R, Redel D A

机构信息

Department of Cardiology, Children's Hospital, University of Bonn, Adenauerallee 119, D-5300, Bonn 1, Germany.

出版信息

Cardiovasc Intervent Radiol. 1996 May-Jun;19(3):170-5. doi: 10.1007/BF02577614.

DOI:10.1007/BF02577614

PMID:8661644

Abstract

PURPOSE

To examine the feasibility of transvenous placement of a new memory-shaped, small, retrievable coil that has a smaller-caliber delivery system than currently available devices, for closure of the patent ductus arteriosus (PDA).

METHODS

Through 4 or 5 Fr vascular sheaths and 4 or 5 Fr end-hold catheters, the coils were delivered and placed in piglets (n = 10) with PDA. The coils were made from 0.018" (0.46 mm) or 0.028" (0.71 mm) stainless steel guidewire. Mounted for delivery, the new device has the appearance of a conventional guidewire. This neonatal PDA model was created without major surgery or drugs by stenting the ductus arteriosus.

RESULTS

The memory-shaped coils were easily delivered. Coils not optimally placed were retrieved and repositioned. Occlusion of the ductus arteriosus as early as a half-hour after delivery was shown angiographically and confirmed by histopathology.

CONCLUSION

This new, small-caliber, simple device was found to be effective for closure of the PDA in this animal model. Longer-term observations are needed.

摘要

目的

研究经静脉置入一种新型记忆形状、小型、可回收线圈的可行性，该线圈具有比现有设备更小口径的输送系统，用于闭合动脉导管未闭（PDA）。

方法

通过4或5 Fr血管鞘和4或5 Fr端持导管，将线圈输送并放置于患有PDA的仔猪（n = 10）体内。线圈由0.018英寸（0.46毫米）或0.028英寸（0.71毫米）不锈钢导丝制成。新装置在输送时安装好，外观类似传统导丝。该新生儿PDA模型通过对动脉导管进行支架置入而创建，无需进行大手术或使用药物。