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动脉粥样硬化性髂动脉狭窄的腔内支架治疗:一项多中心研究的初步报告。

Intraluminal stents in atherosclerotic iliac artery stenosis: preliminary report of a multicenter study.

作者信息

Palmaz J C, Richter G M, Noeldge G, Schatz R A, Robison P D, Gardiner G A, Becker G J, McLean G K, Denny D F, Lammer J

机构信息

Department of Radiology, University of Texas Health Science Center, San Antonio 78284-7800.

出版信息

Radiology. 1988 Sep;168(3):727-31. doi: 10.1148/radiology.168.3.2970098.

DOI:10.1148/radiology.168.3.2970098
PMID:2970098
Abstract

Fifteen patients with symptomatic iliac artery stenosis were treated with intraluminal placement of balloon-expandable stents. Before treatment, 14 patients had intermittent claudication, and one had a limb at risk for amputation. One patient had diabetes mellitus, nine had hypertension, and all were long-term smokers. Two patients had surgical placement of the stent; in one patient this was part of a combined revascularization procedure. All other stents were placed percutaneously. The transstenotic gradient after injection of vasodilating drugs distal to the lesion decreased from a mean of 32.3 mm Hg +/- 16.7 to 3.1 mm Hg +/- 4.2 after stent placement. Ankle-arm Doppler systolic pressure index increased from a mean of 0.68 +/- 0.22 to 0.96 +/- 0.24 after the procedure. The treatment eliminated intermittent claudication in 14 patients and increased exercise tolerance to 500 m in the patient with a limb at risk for amputation before the procedure. The improved condition persisted in all patients during the follow-up of 6-12 months. Stent placement may be a valuable adjunct in the management of iliac artery disease.

摘要

15例有症状的髂动脉狭窄患者接受了球囊扩张支架腔内植入治疗。治疗前,14例患者有间歇性跛行,1例肢体有截肢风险。1例患者患有糖尿病,9例患有高血压,所有患者均为长期吸烟者。2例患者通过手术植入支架;其中1例是联合血运重建手术的一部分。所有其他支架均经皮植入。在病变远端注射血管扩张药物后,跨狭窄压差从平均32.3 mmHg±16.7降至支架植入后的3.1 mmHg±4.2。术后踝臂多普勒收缩压指数从平均0.68±0.22升至0.96±0.24。该治疗消除了14例患者的间歇性跛行,并使术前肢体有截肢风险的患者的运动耐量提高到500米。在6至12个月的随访期间,所有患者的病情均持续改善。支架植入可能是髂动脉疾病治疗中有价值的辅助手段。

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