Nagasawa H, Arakaki Y, Yamada O, Nakajima T, Kamiya T
Department of Pediatrics, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565, Japan.
Pediatr Cardiol. 1996 May-Jun;17(3):169-74. doi: 10.1007/BF02505207.
Previous studies have evaluated left ventricular dimensions in children using two-dimensional echocardiography, but there is little information on gender differences and on the longitudinal development of the dimensions of the left ventricle. Our objective was to assess, by two-dimensional echocardiography, the normal size of the left ventricular end-diastolic dimension (LVDd) in children, its differences by sex, and the rate of its development using height, weight, and body surface area as indices. The study group consisted of 437 patients (264 males, 173 females) with a history of Kawasaki disease but with no coronary artery lesions, as determined by repeated echocardiographic and other examinations. A total of 1595 examinations were done over an average of 6.7 years. The increase in LVDd was significantly more rapid in (1) children below 2 years of age than in older children of either sex and (2) in males who were 11 and 12 years old than in males who were 10 years old. Significant gender differences were observed in the increase in LVDd by all indices (p < 0.001).
以往的研究使用二维超声心动图评估了儿童的左心室大小，但关于性别差异以及左心室大小的纵向发育情况的信息较少。我们的目的是通过二维超声心动图评估儿童左心室舒张末期内径（LVDd）的正常大小、其性别差异，以及以身高、体重和体表面积为指标的发育速率。研究组由437例患者组成（男性264例，女性173例），这些患者有川崎病病史，但经反复超声心动图检查及其他检查确定无冠状动脉病变。平均6.7年共进行了1595次检查。LVDd的增加在以下情况更为迅速：（1）2岁以下儿童比其他年龄段的儿童更快，无论性别；（2）11岁和12岁的男性比10岁的男性更快。所有指标显示LVDd增加存在显著性别差异（p<0.001）。
