LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.

作者信息

Liao X, Ma C, Trask B, Massa H, Gilbert D J, Staudt L M, Jenkins N A, Copeland N G

机构信息

Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI-Frederick Cancer Research & Development Center, Maryland 21702, USA.

出版信息

Mamm Genome. 1996 Jun;7(6):467-8. doi: 10.1007/s003359900137.

DOI:10.1007/s003359900137

PMID:8662235

Abstract

摘要

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LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias.LAF-4编码一种具有反式激活潜能的淋巴核蛋白，该蛋白与AF-4同源，AF-4是在t(4;11)白血病中与MLL融合的基因。

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