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The open brain (opb) mutation maps to mouse chromosome 1.

作者信息

Günther T, Spörle R, Schughart K

机构信息

GSF-National Research Center for Environment and Health, Institute of Mammalian Genetics, Neuherberg, Ingolstädter Landstr. 1, 85758 Oberschleissheim, Germany.

出版信息

Mamm Genome. 1997 Aug;8(8):583-5. doi: 10.1007/s003359900509.

DOI:10.1007/s003359900509
PMID:9250866
Abstract
摘要

相似文献

1
The open brain (opb) mutation maps to mouse chromosome 1.开放脑（opb）突变定位于小鼠1号染色体。
Mamm Genome. 1997 Aug;8(8):583-5. doi: 10.1007/s003359900509.
2
Severe defects in the formation of epaxial musculature in open brain (opb) mutant mouse embryos.
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Genetic landmarks for defects in mouse neural tube closure.小鼠神经管闭合缺陷的遗传标记
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A phenotype-based screen for embryonic lethal mutations in the mouse.基于表型的小鼠胚胎致死突变筛选。
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A rat mutation producing demyelination (dmy) maps to chromosome 17.一种导致脱髓鞘的大鼠突变（dmy）定位于17号染色体。
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Genetic basis of neural tube defects: the mouse gene loop-tail maps to a region of chromosome 1 syntenic with human 1q21-q23.
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引用本文的文献

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Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.小鼠搭便车突变体出现脊柱裂、背腹模式缺陷和多指畸形：鉴定Tulp3为音猬因子信号通路的新型负调控因子。
Hum Mol Genet. 2009 May 15;18(10):1719-39. doi: 10.1093/hmg/ddp075. Epub 2009 Feb 17.
2
A phenotype-based screen for embryonic lethal mutations in the mouse.基于表型的小鼠胚胎致死突变筛选。
Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7485-90. doi: 10.1073/pnas.95.13.7485.

本文引用的文献

1
The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney.小鼠Pax2(1Neu)突变与肾-眼裂综合征家族中的一种人类PAX2突变相同，会导致脑、耳、眼和肾的发育缺陷。
Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13870-5. doi: 10.1073/pnas.93.24.13870.
2
Mice as models of human developmental disorders: natural and artificial mutants.作为人类发育障碍模型的小鼠：自然突变体和人工突变体。
Curr Opin Genet Dev. 1996 Jun;6(3):289-94. doi: 10.1016/s0959-437x(96)80004-9.
3
The dysmorphic human-mouse homology database (DHMHD): an interactive World-Wide Web resource for gene mapping.
畸形人类-小鼠同源性数据库（DHMHD）：一个用于基因定位的交互式万维网资源。
J Med Genet. 1996 Apr;33(4):289-94. doi: 10.1136/jmg.33.4.289.
4
LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.
Mamm Genome. 1996 Jun;7(6):467-8. doi: 10.1007/s003359900137.
5
Severe defects in the formation of epaxial musculature in open brain (opb) mutant mouse embryos.
Development. 1996 Jan;122(1):79-86. doi: 10.1242/dev.122.1.79.
6
A Macintosh program for storage and analysis of experimental genetic mapping data.一个用于存储和分析实验性基因图谱数据的麦金塔程序。
Mamm Genome. 1993;4(6):303-13. doi: 10.1007/BF00357089.
7
A genetic map of the mouse with 4,006 simple sequence length polymorphisms.一张具有4006个简单序列长度多态性的小鼠遗传图谱。
Nat Genet. 1994 Jun;7(2 Spec No):220-45. doi: 10.1038/ng0694supp-220.
8
Open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord.开放性脑，一种患有严重神经管缺陷的新型小鼠突变体，在发育中的脊髓中表现出基因表达模式的改变。
Development. 1994 Nov;120(11):3119-30. doi: 10.1242/dev.120.11.3119.
9
The embryonic development of mammalian neural tube defects.哺乳动物神经管缺陷的胚胎发育
Prog Neurobiol. 1990;35(5):363-403. doi: 10.1016/0301-0082(90)90037-h.
10
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.一种通过哺乳动物表达从B细胞中克隆出的新型白细胞介素-1受体，在多种细胞类型中表达。
EMBO J. 1991 Oct;10(10):2821-32. doi: 10.1002/j.1460-2075.1991.tb07831.x.