Risum O, Abdelnoor M, Svennevig J L, Levorstad K, Nitter-Hauge S
Surgical Dept A, Rikshospitalet, University of Oslo, Norway.
Eur J Cardiothorac Surg. 1996;10(3):173-8. doi: 10.1016/s1010-7940(96)80293-4.
The long-term results of 1025 patients, 912 men and 113 women, undergoing coronary artery bypass grafting (CABG) at the Cardiovascular Unit of Rikshospitalet, Oslo, between 1982 and 1986, were analyzed on factors associated with the return of angina pectoris and of non-fatal post CABG myocardial infarction. The closing date was 1st January 1993, with a mean follow-up time of 7.4 years. Recurrent angina pectoris was experienced by 118 (11.6%) patients and 102 (10%) patients experienced non-fatal post CABG myocardial infarction during the observation period. Altogether 30 possible risk factors were analyzed. The cumulative incidence of recurrent angina was initially low after operation, followed by a rise after 4 years. One, 5 and 10 years after the operation, survival free from angina rates were 97.8%, 91.8% and 80.6%, respectively. The cumulative incidence of post CABG myocardial infarction was also low initially, followed by a rise after 4 years. The survival free of non-fatal post CABG myocardial infarction rate was 98.9%, 96% and 83.5%, at 1, 5 and 10 years after surgery, respectively. The incremental risk factor of recurrent angina pectoris was hypertension. The independent risk factors of non-fatal post CABG myocardial infarction were hypertension and preoperative stenosis of the left-sided, versus right-sided, coronary arteries. The study emphasizes the favorable effect of coronary bypass surgery on the functional outcome in patients with symptomatic coronary artery disease.
对1982年至1986年间在奥斯陆国家医院心血管科接受冠状动脉旁路移植术（CABG）的1025例患者（912例男性和113例女性）的长期结果进行了分析，探讨与心绞痛复发及CABG术后非致命性心肌梗死相关的因素。截止日期为1993年1月1日，平均随访时间为7.4年。在观察期内，118例（11.6%）患者出现复发性心绞痛，102例（10%）患者发生CABG术后非致命性心肌梗死。共分析了30个可能的危险因素。复发性心绞痛的累积发生率术后初期较低，4年后上升。术后1年、5年和10年无心绞痛生存率分别为97.8%、91.8%和80.6%。CABG术后心肌梗死的累积发生率初期也较低，4年后上升。术后1年、5年和10年无CABG术后非致命性心肌梗死生存率分别为98.9%、96%和83.5%。复发性心绞痛的增量危险因素是高血压。CABG术后非致命性心肌梗死的独立危险因素是高血压和左侧冠状动脉与右侧冠状动脉相比术前存在狭窄。该研究强调了冠状动脉搭桥手术对有症状冠状动脉疾病患者功能转归的有利影响。
