Landymore R, Murphy J T, Hall R, Islam M
Department of Cardiac Sciences, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
Eur J Cardiothorac Surg. 1996;10(3):179-84. doi: 10.1016/s1010-7940(96)80294-6.
Forty patients were randomized to receive antegrade multidose warm (WBC) or cold blood cardioplegia (CBC) during coronary artery bypass. Cardioplegia was infused at a predetermined dose every 10 min during cardioplegia arrest and core temperature was maintained at 37 degrees C in both groups during extracorporeal circulation. Patient profiles were similar in the two groups. Cardiac index, left ventricular stroke work index, and myocardial oxygen consumption were measured before bypass and during the first 7 h of reperfusion. There was no significant difference in myocardial metabolic and function recovery, the incidence of myocardial infarction, low cardiac output or death. Our data suggests that similar protection is provided with the two techniques of myocardial protection.
40例患者在冠状动脉搭桥手术中被随机分为两组，分别接受顺行多剂量温血（WBC）或冷血心脏停搏液（CBC）灌注。在心脏停搏期间，每隔10分钟以预定剂量灌注心脏停搏液，体外循环期间两组的核心体温均维持在37摄氏度。两组患者的基本情况相似。在搭桥手术前以及再灌注的前7小时内，测量心脏指数、左心室每搏功指数和心肌耗氧量。心肌代谢和功能恢复、心肌梗死发生率、低心排血量或死亡率方面均无显著差异。我们的数据表明，这两种心肌保护技术提供了相似的保护效果。
