Brenner D J, Smith F A
Phys Med Biol. 1977 May;22(3):451-65. doi: 10.1088/0031-9155/22/3/006.
Computer calculations are made of the dose and LET distributions due to neutrons and photons produced when negative pions are stopped in a phantom. When negative pions are stopped in a material they undergo nuclear capture, resulting in the disintegration of the nucleus and the emission of short range charged particles and longer range neutrons and photons. The uncharged radiation constitutes a potentially large source of dose outside the treatment volume. A simple phantom consisting of a 0-25 m cube of either tissue or bone-equivalent material is set up with a 0-05 m cube in the centre to represent the treatment volume. Neutrons and photons are started in this central volume and transported across the phantom using Monte Carlo transport codes. Several different initial energy spectra for the neutrons are used, taken from experimental and theoretical data. These different spectra are found to give significant differences in dose, though the distance to the 80% dose level is always about 0-015 m. Order of magnitude differences in some LET regions are also found. The dose deposited by neutrons in bone is about 24% less than in soft tissue, the photon dose being small compared with the neutron dose.
对负π介子在模体中停止时产生的中子和光子的剂量及传能线密度(LET)分布进行了计算机计算。当负π介子在一种物质中停止时,它们会发生核俘获,导致原子核解体并发射短程带电粒子以及长程中子和光子。不带电辐射在治疗体积之外构成了一个潜在的大剂量源。构建了一个简单的模体,它由一个边长0 - 25米的组织或骨等效材料立方体组成,中心有一个边长0 - 05米的立方体来代表治疗体积。中子和光子在这个中心体积内产生,并使用蒙特卡罗输运代码在整个模体中进行输运。使用了从实验和理论数据中获取的几种不同的中子初始能谱。发现这些不同的能谱在剂量上有显著差异,尽管到80%剂量水平的距离总是约为0 - 015米。在一些LET区域也发现了数量级的差异。中子在骨中沉积的剂量比在软组织中约少24%,与中子剂量相比,光子剂量较小。