Rosbash M
Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusets 02254, USA.
Curr Opin Genet Dev. 1995 Oct;5(5):662-8. doi: 10.1016/0959-437x(95)80037-9.
Circadian rhythms are virtually ubiquitous in eukaryotes and have been shown to exist even in some prokaryotes. The generally accepted view is that these rhythms are generated by an endogenous clock. Recent progress, especially in the Drosophila, Neurospora and mouse systems, has revealed new clock components and mechanisms. These include the mouse clock gene, the Drosophila timeless gene, and the role of light in Neurospora.
昼夜节律在真核生物中几乎无处不在,甚至在一些原核生物中也已被证明存在。普遍接受的观点是,这些节律是由一个内源性生物钟产生的。最近的进展,特别是在果蝇、脉孢菌和小鼠系统中的进展,揭示了新的生物钟组件和机制。这些包括小鼠生物钟基因、果蝇的timeless基因以及光在脉孢菌中的作用。