MacLaren D, Miles A, O'Neill I, Critchley M, Grime S, Stockdale H
School of Human Sciences, Liverpool John Moores University, United Kingdom.
Br J Sports Med. 1996 Mar;30(1):20-3. doi: 10.1136/bjsm.30.1.20.
To investigate the repeatability of continual assessment of the gastric emptying rates of carbohydrate solutions in exercising subjects using 99mtechnetium labelling.
Gastric emptying of a 5% glucose solution and an iso-osmotic maltodextrin solution was measured using 3 MBq of 99mtechnetium labelled diethylene triamine penta-acetic acid (DTPA) and continuous gamma camera imaging in five male subjects. The subjects performed four 1 h trials at 70% VO2 peak on a cycle ergometer. After 15 min, 200 ml of a radiolabelled solution of glucose or maltodextrin were ingested in a blind crossover protocol. The two solutions were each ingested on separate occasions (trial 1 and trial 2) to establish repeatability.
Statistical analysis showed no differences between trial 1 and trial 2 for both solutions. There were no significant differences for the emptying rates between the two test solutions.
Posterior imaging using a computer linked gamma camera following the ingestion of 99mtechnetium labelled DTPA mixed with carbohydrate solutions provides a repeatable method of assessing gastric emptying characteristics in exercising subjects. This technique showed no significant differences between the emptying rates of a single dose of iso-osmotic glucose or maltodextrin solution.
利用99m锝标记研究运动受试者碳水化合物溶液胃排空率连续评估的可重复性。
在5名男性受试者中，使用3MBq的99m锝标记二乙三胺五乙酸（DTPA）和连续γ相机成像测量5%葡萄糖溶液和等渗麦芽糊精溶液的胃排空。受试者在功率自行车上以70%最大摄氧量进行4次1小时试验。15分钟后，按照盲法交叉方案摄入200ml放射性标记的葡萄糖或麦芽糊精溶液。两种溶液分别在不同时间摄入（试验1和试验2）以确定可重复性。
统计分析表明两种溶液的试验1和试验2之间无差异。两种测试溶液的排空率无显著差异。
摄入99m锝标记的DTPA与碳水化合物溶液混合后，使用计算机连接的γ相机进行后位成像，为评估运动受试者的胃排空特征提供了一种可重复的方法。该技术显示单剂量等渗葡萄糖或麦芽糊精溶液的排空率无显著差异。
