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前括约肌成形术的生理及临床结果

Physiological and clinical outcome of anterior sphincteroplasty.

作者信息

Oliveira L, Pfeifer J, Wexner S D

机构信息

Department of Colorectal Surgery, Cleveland Clinic Florida, Fort Lauderdale 33309, USA.

出版信息

Br J Surg. 1996 Apr;83(4):502-5. doi: 10.1002/bjs.1800830421.

DOI:10.1002/bjs.1800830421
PMID:8665241
Abstract

A total of 55 women underwent sphincteroplasty for the treatment of faecal incontinence related to anterior defects. Patients were followed prospectively for a mean of 29 months to evaluate the outcome overall and according to age. All patients were evaluated clinically by means of a questionnaire and graded using an incontinence scoring system ranging from 0 (perfect continence) to 20 (complete incontinence). Some 52 patients (95 per cent) had had a previous vaginal delivery and 30 (55 per cent) had a history of previous anal sphincter repair. Physiological and functional parameters in patients with a successful outcome (n = 39) were compared with those in patients with a poor outcome (n = 16). The results were also compared in patients under (n = 39) and over (n = 16) 60 years of age. Overall, patients with a successful outcome had a significant change in mean and maximal resting and squeeze pressures. These changes correlated well with the increase in the high-pressure zone (HPZ) length from 1.0-2.2 cm (P = 0.0002) and with functional outcome (change in incontinence score from 15.3 to 5.8; P < 0.0001). In patients over 60 years of age, a significant change in mean squeeze pressure (P = 0.03) and HPZ length (P = 0.01) was noted and correlated with functional outcome (change in incontinence score from 14.3 to 6.4; P < 0.0001). A successful outcome after anterior sphincteroplasty is related to improvement in sphincter function even in an older population. These results demonstrate that age itself does not seem to be a predictor of poor outcome. Patients should not be denied a repair exclusively on grounds of age.

摘要

共有55名女性接受了括约肌成形术,以治疗与前部缺损相关的大便失禁。对患者进行了平均29个月的前瞻性随访,以评估总体结果以及按年龄分组的结果。所有患者均通过问卷调查进行临床评估,并使用从0(完全控便)到20(完全失禁)的失禁评分系统进行分级。约52名患者(95%)曾有过阴道分娩史,30名患者(55%)有过肛门括约肌修复史。将手术成功的患者(n = 39)与手术效果不佳的患者(n = 16)的生理和功能参数进行比较。还对60岁以下(n = 39)和60岁以上(n = 16)的患者结果进行了比较。总体而言,手术成功的患者在平均和最大静息及收缩压力方面有显著变化。这些变化与高压区(HPZ)长度从1.0 - 2.2 cm的增加密切相关(P = 0.0002),并与功能结果相关(失禁评分从15.3降至5.8;P < 0.0001)。在60岁以上的患者中,平均收缩压力(P = 0.03)和HPZ长度(P = 0.01)有显著变化,并与功能结果相关(失禁评分从14.3降至6.4;P < 0.0001)。即使在老年人群中,前部括约肌成形术后的成功结果也与括约肌功能的改善有关。这些结果表明,年龄本身似乎并不是手术效果不佳的预测因素。不应仅以年龄为由拒绝患者进行修复手术。

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