Woźniak W, Izbicki T, Rychlowska M, Niedzielski P
Department of Oncological Surgery, National Research Institute of Mother and Child, Warsaw, Poland.
J Surg Oncol. 1996 Jul;62(3):183-5. doi: 10.1002/(SICI)1096-9098(199607)62:3<183::AID-JSO7>3.0.CO;2-3.
The application of intensive multimodality therapy has made possible salvage surgery in bone tumors. Reconstruction of the removed part of bone is the great problem, especially in fast-growing children. In three patients (two osteosarcomas and one Ewing's sarcoma), the tumor was confined to the proximal half part of humerus, without invasion of shoulder joint. After induction chemotherapy, reduction of tumor size was observed both clinically and radiologically. During the operation, wide resection of the tumor together with a 12- to 14-cm-long fragment of humerus, was performed. Afterward, the clavicle was rotated in the place of the removed bone, with preservation of the coracoacromial ligament. The humeral stump and clavicle were fixed with the use of metal plate. Adjuvant chemotherapy was used a few days following surgery. After 3 months, the osteosynthesis had healed. The movements in shoulder joint are limited, but functions of elbow joint remained normal. All children are alive and disease free. Reconstruction of humerus with clavicle rotation is possible when the proximal bone loss is not longer than 10-14 cm. This method seems to be an alternative to allogeneic grafts and endoprostheses.
强化多模式治疗的应用使得骨肿瘤的保肢手术成为可能。骨切除部分的重建是一个重大问题,尤其是在快速生长的儿童中。在三名患者(两名骨肉瘤和一名尤因肉瘤)中,肿瘤局限于肱骨近端半部,未侵犯肩关节。诱导化疗后,临床和影像学上均观察到肿瘤大小缩小。手术期间,对肿瘤连同12至14厘米长的肱骨片段进行了广泛切除。随后,将锁骨旋转至切除骨的位置,保留喙肩韧带。肱骨残端和锁骨用金属板固定。术后几天使用辅助化疗。3个月后,骨合成愈合。肩关节活动受限,但肘关节功能保持正常。所有儿童均存活且无疾病。当近端骨缺损不超过10至14厘米时,用锁骨旋转重建肱骨是可行的。这种方法似乎是同种异体移植和人工假体的一种替代方法。