Elsässer E
Recent Results Cancer Res. 1977(60):163-75. doi: 10.1007/978-3-642-81095-4_18.
Tumors of the epididymis, both primary and secondary, whether benign or malignant are very rare. The elements of the spermatic duct system, whether inside the testis or outside it in the epididymis and spermatic cord, exhibit only 1/20th of that of the germinal epithelium. In accordance with the mesodermal, or mesothelial origin of the whole spermatic ducr system, tumors of the epididymis and spermatic cord are - with few exceptions - mesenchymal tumors, the most frequent of these being the so-called adenomatoid tumor, a benign slowly growing tumor. With regard to the relative frequency of the various extratesticular tumors, a British panel has shown that one quarter of its cases are adenomatoid tumors, a second quarter sarcomas of children and juveniles (rhabdomyosarcomas and embryonic sarcomas), a third quarter sarcomas of adults and aged, while the last quarter includes simple benign mesenchymal tumors, mixed tumors, metastatic tumors, and others. There is only one extremely rare epithelial tumor of the epididymis, the papillary cystadenoma, which seems to be a partial menifestation or forme fuste of Hippel-Lindau's disease. So far only 40 cases have been described in the world literature. Therapy of intrascrotal but extratesticular tumors always ought to be surgical: if the tumor proves to be benign, simple excision suffices. In cases of malignancy, immediate inguinal lymphadenectomy and - as with testicular tumors - lymphography followed by retroperitoneal lymphadenectomy. Whether one should, in principle, then continue treatment either chemotherapeutically or radiotherapeutically, or do so only when there is evidence of metastasis, is a question whiich still remains open.
附睾肿瘤,无论是原发性还是继发性,无论良性还是恶性都非常罕见。精索系统的组成部分,无论在睾丸内部还是在睾丸外部的附睾和精索中,其发生率仅为生殖上皮的1/20。根据整个精索系统的中胚层或间皮起源,附睾和精索肿瘤除少数例外均为间叶组织肿瘤,其中最常见的是所谓的腺瘤样肿瘤,一种生长缓慢的良性肿瘤。关于各种睾丸外肿瘤的相对发生率,一个英国小组表明,其四分之一的病例是腺瘤样肿瘤,四分之一是儿童和青少年的肉瘤(横纹肌肉瘤和胚胎性肉瘤),四分之一是成人和老年人的肉瘤,而最后四分之一包括单纯性良性间叶组织肿瘤、混合性肿瘤、转移性肿瘤及其他。附睾仅有1种极为罕见的上皮性肿瘤,即乳头状囊腺瘤,它似乎是希佩尔-林道病的部分表现或原始形式。迄今为止,世界文献中仅描述了40例。阴囊内但睾丸外肿瘤的治疗通常应采用手术:如果肿瘤被证明是良性的,单纯切除即可。对于恶性肿瘤病例,应立即进行腹股沟淋巴结清扫术,并且与睾丸肿瘤一样,先行淋巴造影,然后进行腹膜后淋巴结清扫术。原则上,此后是应继续进行化疗或放疗,还是仅在有转移证据时才进行,这一问题仍然悬而未决。