Fallert M, Böhmer G, Dinse H R
Respir Physiol. 1977 Apr;29(2):143-9. doi: 10.1016/0034-5687(77)90087-1.
Single bulbar respiratory unit activity was recorded in urethane-anesthetized rabbits. During artificial ventilation, reflex contractions of the diaphragm were elicited by the forced deflations of the respirator. Out of 44 neurons, four I, one E and two EI units exhibited a shift of their discharge relative to the contractile phase of the diaphragm, compared to normal respiration. During hypocapnic apnea, some I, IE and E neurons became silent. Other cells belonging to all phase types, however, continued to fire tonically at a rate less than the peak rate in normal bursts. When rhythmic respiration resumed after termination of the apneic pause, five (I, IE and E) units exhibited a transient phase shift of their burst discharge compared to normal respiration. The results of simultaneous recordings of two neurons belonging to different phase types are compatible with the assumption that inspiratory units are periodically inhibited by inspiratory-expiratory cells.
在氨基甲酸乙酯麻醉的兔子中记录单个延髓呼吸单位的活动。在人工通气期间，呼吸器的强制放气引发膈肌的反射性收缩。在44个神经元中，与正常呼吸相比，4个I型、1个E型和2个EI型单位的放电相对于膈肌收缩期发生了偏移。在低碳酸血症性呼吸暂停期间，一些I型、IE型和E型神经元变得沉默。然而，属于所有相位类型的其他细胞继续以低于正常爆发峰值速率的频率进行紧张性放电。当呼吸暂停期结束后节律性呼吸恢复时，5个（I型、IE型和E型）单位的爆发放电与正常呼吸相比出现了短暂的相位偏移。对属于不同相位类型的两个神经元进行同步记录的结果与吸气单位受到吸气 - 呼气细胞周期性抑制的假设相符。
