op de Coul M E, Kardos G
Academisch Ziekenhuis Vrije Universiteit, afd. Kindergeneeskunde, Amsterdam.
Ned Tijdschr Geneeskd. 1996 Apr 6;140(14):785-7.
In a 14-year old boy admitted because of fever of unknown origin chronic meningococcaemia was diagnosed. He had suffered for the last four months from periods of high fever accompanied by skin rash and arthralgia. Blood culture showed the presence of Neisseria meningitidis. Cerebrospinal fluid culture remained negative. Following the administration of high-dose intravenous benzylpenicillin a prompt resolution of all signs and symptoms was observed. No immunological abnormalities were found. Chronic meningococcaemia can be a--nowadays uncommon--cause of fever of unknown origin.
一名14岁男孩因不明原因发热入院,被诊断为慢性脑膜炎球菌血症。在过去四个月里,他一直遭受高热,伴有皮疹和关节痛。血培养显示存在脑膜炎奈瑟菌。脑脊液培养仍为阴性。给予大剂量静脉注射苄星青霉素后,所有症状和体征迅速消失。未发现免疫异常。慢性脑膜炎球菌血症可能是——如今并不常见——不明原因发热的一个原因。