Bertola G, Torchio G, Bocchia M, Meregalli M, Santangelo M
II Divisione di Medicina, Ospedale Santa Corona Garbagnate Milanese (Milano).
Minerva Med. 1996 Mar;87(3):105-8.
A case of temporal arteritis is described in a woman of 67, affected by non insulin dependent diabetes mellitus, associated with polymyalgia rheumatica and complicated by angina pectoris. Angina, which appeared a few days after diagnosis, was coupled with electrocardiographic alterations, which did not seem sensitive to nitrates but went back when steroid at full dose was added. The patient was also affected by Basedow disease, which was present during the whole course of the vasculitis. Furthermore islet-cell antibodies (ICA) were present. HLA typing showed the presence of the B8, DR3 haplotype. The patient died after 22 months from the diagnosis of digestive hemorrhage, probably favoured by extended cortisone therapy, while signs of arteritis were still evident.
本文描述了一名67岁女性颞动脉炎病例，该患者患有非胰岛素依赖型糖尿病，伴有风湿性多肌痛，并并发心绞痛。心绞痛在诊断后几天出现，伴有心电图改变，这些改变对硝酸盐似乎不敏感，但在加用全剂量类固醇后恢复。患者还患有弥漫性毒性甲状腺肿，在血管炎的整个病程中都存在。此外，还存在胰岛细胞抗体（ICA）。HLA分型显示存在B8、DR3单倍型。患者在诊断为消化性出血22个月后死亡，可能是长期使用可的松治疗所致，而动脉炎迹象仍很明显。
