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[30毫克辛诺昔康治疗骨关节炎患者的临床评估。一项双盲对照研究]

[Clinical evaluation of cinnoxicam 30 mg in patients with osteoarthrosis. A double-blind controlled study].

作者信息

Bestetti F

机构信息

Clinica Ortopedica, Ospedale San Gerardo, Monza (Milano).

出版信息

Minerva Med. 1996 Mar;87(3):117-22.

PMID:8668288
Abstract

We tested the therapeutic response of osteoarthrosis subjects to piroxicam cinnamate 30 mg tablets (Sinartrol). The double-blind study was conducted in 2 homogeneous groups of 30 patients each treated with piroxicam cinnamate one 30 mg tablet twice daily for 2 days followed by 1 tablet daily for 13 more days and with piroxicam cinnamate 20 mg tablets (according to the same posologic scheme) respectively. The results obtained demonstrate the efficacy of this new piroxicam cinnamate formulation which led to a significant clinical improvement, already evident after 2 days of treatment and even more evident at the end of therapy. Patients' compliance to treatment was good and side effects were scarce and spontaneously subsiding.

摘要

我们测试了骨关节炎患者对30毫克辛诺昔康片(西那曲尔)的治疗反应。这项双盲研究在两组各30名患者中进行,两组患者分别每日两次服用1片30毫克辛诺昔康片,持续2天,随后每日1片,再持续13天;另一组每日两次服用1片20毫克辛诺昔康片(按照相同的给药方案)。所获得的结果证明了这种新的辛诺昔康制剂的疗效,治疗2天后临床改善就已显著,治疗结束时更加明显。患者对治疗的依从性良好,副作用很少且能自行消退。

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