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在疫苗接种覆盖率高的人群中发生麻疹疫情期间的临床和流行病学发现。

Clinical and epidemiological findings during a measles outbreak occurring in a population with a high vaccination coverage.

作者信息

de Oliveira S A, Soares W N, Dalston M O, de Almeida M T, Costa A J

机构信息

Disciplina de Doenças Infecciosas e Parasitárias, Universidade Federal Fluminense Niterói, RJ, Brasil.

出版信息

Rev Soc Bras Med Trop. 1995 Oct-Dec;28(4):339-43. doi: 10.1590/s0037-86821995000400006.

DOI:10.1590/s0037-86821995000400006
PMID:8668833
Abstract

From March 1991 to April 1992, 250 measles suspected cases were studied in the Municipality of Niterói, State of Rio de Janeiro. The median age found was 11 years and 76.0% of the cases were in school age children. Exposure histories were present in 149 patients and schools were the most frequent sites of transmission (45.0%). Vaccination status was known for 127 studied cases and 76.4% of them had received measles vaccine before their first birthday. One or more complications were reported for 68 cases and in 8.9% of the studied cases hospitalization was required. Frequency of complications varied according to each age group studied and were more commonly encountered among children < 1 year of age (55.6%). The history of previous vaccination did not diminish the number of complications of the cases studied. The results of this work show changes in age distribution of measles leading to sizeable outbreaks among teenagers and young adults.

摘要

1991年3月至1992年4月,对里约热内卢州尼泰罗伊市的250例麻疹疑似病例进行了研究。发现的中位年龄为11岁,76.0%的病例为学龄儿童。149例患者有暴露史,学校是最常见的传播场所(45.0%)。已知127例研究病例的疫苗接种状况,其中76.4%在一岁前接种过麻疹疫苗。68例报告了一种或多种并发症,8.9%的研究病例需要住院治疗。并发症的发生率因所研究的每个年龄组而异,在<1岁的儿童中更常见(55.6%)。既往接种疫苗史并未减少所研究病例的并发症数量。这项工作的结果显示麻疹的年龄分布发生了变化,导致青少年和年轻人中出现了大规模疫情。

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