Baruch H H, Firooznia H, Sackler J P, Genieser N B, Rafii M, Golimbu C
Rev Interam Radiol. 1977 Apr;2(2):77-81.
Pulmonary disorders occur in 25 to 47 per cent of the patients with Sjogren's Syndrome. These are of two types: 1. related to the major connective tissue disorders which commonly accompany this syndrome, and 2. secondary to the peculiar underlying pathology of Sjogren's Syndrome i.e. sicca disorders of the lung. The latter is the more frequent type, occurring mainly in patients with protected sicca complex unaccompanied by a systemic connective tissue disorder, and consists of chronic bronchitis, subsegmental atelectasis, pneumonia, bronchiectasis, lymphoproliferative pulmonary infiltrates and chronic interstitial pneumonitis which may lead to pulmonary fibrosis. 21 cases of Sjogren's Syndrome, 9 of whom had evidence of pulmonary abnormality, are presented, including a case of interstitial pneumonitis leading to diffuse interstitial pulmonary fibrosis. A review of the literature is included.
干燥综合征患者中25%至47%会出现肺部疾病。这些疾病有两种类型：1. 与该综合征常见的主要结缔组织疾病相关；2. 继发于干燥综合征独特的潜在病理，即肺部干燥症。后者更为常见，主要发生在无系统性结缔组织疾病的局限性干燥综合征患者中，包括慢性支气管炎、亚段性肺不张、肺炎、支气管扩张、淋巴增殖性肺浸润和慢性间质性肺炎，后者可能导致肺纤维化。本文报告了21例干燥综合征患者，其中9例有肺部异常证据，包括1例导致弥漫性间质性肺纤维化的间质性肺炎病例，并对相关文献进行了综述。
