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[由偶发分枝杆菌引起的肺部分枝杆菌病:对经典抗结核药物的体外敏感性及临床进展]

[Pulmonary mycobacteriosis due to Mycobacterium xenopi" in-vitro sensitivity to classical antitubercular agents and clinical development].

作者信息

Baugnée P E, Pouthier F, Delaunois L

机构信息

Service de Pneumologie, Cliniques Universitaires UCL de Mont-Godinne, Yvoir.

出版信息

Acta Clin Belg. 1996;51(1):19-27.

PMID:8669159
Abstract

Out of 11 patients suffering from Mycobacterium xenopi lung disease, 9 were treated with an empiric antituberculous triple chemotherapy until specific identification and antibiogram were available. Despite the important "in vitro" resistance to drugs, most of the patients improved; in the other patients, the impairment was always due to the underlying pathology. We conclude that the "in vivo" response of M. xenopi infections to antituberculous drugs is little influenced by the "in vitro" sensitivity.

摘要

在11例患有偶发分枝杆菌肺病的患者中,9例接受了经验性抗结核三联化疗,直到获得细菌的特异性鉴定和药敏试验结果。尽管该菌对药物有重要的“体外”耐药性,但大多数患者病情有所改善;在其他患者中,病情损害总是由潜在病理状况所致。我们得出结论,偶发分枝杆菌感染对抗结核药物的“体内”反应受“体外”敏感性的影响很小。

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