Rumpler W V, Rhodes D G, Baer D J, Conway J M, Seale J L
Beltsville Human Nutrition Research Center, Diet and Human Performance Laboratory, US Department of Agriculture, MD 20705, USA.
Am J Clin Nutr. 1996 Jul;64(1):108-14. doi: 10.1093/ajcn/64.1.108.
We investigated the effects of an equal-energetic substitution of ethanol for dietary carbohydrate in high-and low-fat diets on energy expenditure and body composition. During the controlled feeding study, subjects maintained their weights and consumed only food and drink provided by the US Department of Agriculture Beltsville Human Nutrition Research Center's Diet Study Facility. Subjects (16 men and 32 women) were divided equally into two groups and consumed either a high-or low-fat diet for 16 wk. The feeding period was divided into two 8-wk periods during which either ethanol or carbohydrate was added to the diet (5% of total daily energy intake) in a crossover design. The metabolizable energy content of the diets (with supplements) was determined for all subjects through measurement of total food intake and fecal and urinary losses for 7 d during both 8-wk periods. Energy expenditure, measured for 24 h in a room calorimeter at the end of each 8-wk period, was the same for both periods. Metabolizable energy intake and changes in total-body energy content were used to calculate the total amount of energy expended by each subject for 7 wk during each 8-wk period. Total energy expenditure for 7 wk was the same when subjects consumed either ethanol or carbohydrate. These data clearly show that on an energy basis ethanol and carbohydrate are utilized in the diet with the same efficiency. These data are consistent with the efficiency of use of alcohol for maintenance of metabolizable energy being the same as that for carbohydrate.
我们研究了在高脂和低脂饮食中用等量能量的乙醇替代膳食碳水化合物对能量消耗和身体成分的影响。在对照喂养研究期间，受试者维持体重，仅食用美国农业部贝尔茨维尔人类营养研究中心饮食研究设施提供的食物和饮料。受试者（16名男性和32名女性）平均分为两组，食用高脂或低脂饮食16周。喂养期分为两个8周阶段，采用交叉设计，在此期间，饮食中添加乙醇或碳水化合物（占每日总能量摄入的5%）。通过测量两个8周阶段中7天的总食物摄入量以及粪便和尿液损失，确定了所有受试者饮食（含补充剂）的可代谢能量含量。在每个8周阶段结束时，在房间热量计中测量24小时的能量消耗，两个阶段相同。可代谢能量摄入量和全身能量含量的变化用于计算每个受试者在每个8周阶段中7周内消耗的总能量。当受试者食用乙醇或碳水化合物时，7周的总能量消耗相同。这些数据清楚地表明，在能量基础上，饮食中乙醇和碳水化合物的利用效率相同。这些数据与酒精用于维持可代谢能量的效率与碳水化合物相同一致。
