Walsh L J, L'Estrange P R, Seymour G J
Department of Dentistry, University of Queensland.
Aust Dent J. 1996 Apr;41(2):75-9. doi: 10.1111/j.1834-7819.1996.tb05916.x.
Microscope endoscopy is a technique which allows high resolution, non-invasive examination of soft tissues. This study employed microscope endoscopy to examine the process of healing following exposure of the oral mucosa to carbon dioxide laser radiation. On the wound boundaries, cellular debris and the laser-induced char layer were shed as epithelial migration occurred. Wounds healed by secondary intention, with complete epithelial closure by 72 hours. A marked vascular response was evident from 6 to 48 hours following wounding, a time period coincident with the known pattern of blood vessel activation and infiltration of the wound site by leukocytes. The use of microscope endoscopy as an adjunct to biopsy and other invasive diagnostic methods in the assessment and follow-up of soft tissue pathology may have value in clinical practice.
显微内镜检查是一种能够对软组织进行高分辨率、非侵入性检查的技术。本研究采用显微内镜检查来观察口腔黏膜暴露于二氧化碳激光辐射后的愈合过程。在伤口边界处，随着上皮迁移的发生，细胞碎片和激光诱导的焦痂层脱落。伤口通过二期愈合，在72小时时上皮完全闭合。受伤后6至48小时可见明显的血管反应，这一时间段与已知的血管激活模式以及白细胞浸润伤口部位的时间一致。在软组织病理学评估和随访中，将显微内镜检查作为活检和其他侵入性诊断方法的辅助手段在临床实践中可能具有价值。
