Deschamps F J, Turpin J C
Department of Occupational Diseases, Hopital Maison Blanche, Reims, France.
Occup Med (Lond). 1996 Feb;46(1):89-90. doi: 10.1093/occmed/46.1.89.
There have been over 300 cases of methyl bromide poisoning reported in the literature. The first objective of this case report was to bring out an experience with the false belief that work in a closed space is safe when accompanied by the use of a cartridge respirator with activated charcoal. The second objective of this article was to demonstrate the marked toxicity of methyl bromide with the potential to cause long-term neurological damage. Two experienced fumigation workers (equipped with rapidly saturable respiratory cartridges) entered a building where the concentration of methyl bromide was 17g x m-3 instead of the advised 20mg x m-3. They felt rapidly unwell and complained of nausea and shortness of breath, followed for one them by generalized convulsions. Five months later this last man was still bedridden. The other worker had almost no after-effects. The highest bromide level was found in the blood and also in the activated charcoal cartridge of the most injured worker. There was a relationship between methyl bromide level exposure and neurological damage importance.
文献中已报道了300多例溴甲烷中毒病例。本病例报告的首要目的是揭示一种错误观念的经历，即认为在封闭空间工作时，使用装有活性炭的滤毒罐呼吸器就安全。本文的第二个目的是证明溴甲烷具有显著毒性，有可能导致长期神经损伤。两名经验丰富的熏蒸工人（配备了快速饱和的呼吸滤毒罐）进入一栋建筑物，其中溴甲烷浓度为17g/m³，而非建议的20mg/m³。他们很快感到不适，出现恶心和呼吸急促症状，其中一人随后全身抽搐。五个月后，最后这名男子仍卧床不起。另一名工人几乎没有后遗症。在受伤最严重的工人的血液以及活性炭滤毒罐中发现了最高的溴化物水平。溴甲烷暴露水平与神经损伤严重程度之间存在关联。
