Calvert G M, Mueller C A, Fajen J M, Chrislip D W, Russo J, Briggle T, Fleming L E, Suruda A J, Steenland K
Division of Surveillance, Hazard Evaluations and Field Studies, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA.
Am J Public Health. 1998 Dec;88(12):1774-80. doi: 10.2105/ajph.88.12.1774.
This study assessed the health effects associated with occupational exposure to methyl bromide and sulfuryl fluoride among structural fumigation workers.
A cross-sectional study of 123 structural fumigation workers and 120 referents in south Florida was conducted. Nerve conduction, vibration, neurobehavioral, visual, olfactory, and renal function testing was included.
The median lifetime duration of methyl bromide and sulfuryl fluoride exposure among workers was 1.20 years and 2.85 years, respectively. Sulfuryl fluoride exposure over the year preceding examination was associated with significantly reduced performance on the Pattern Memory Test and on olfactory testing. In addition, fumigation workers had significantly reduced performance on the Santa Ana Dexterity Test of the dominant hand and a nonsignificantly higher prevalence of carpal tunnel syndrome than did the referents.
Occupational sulfuryl fluoride exposures may be associated with subclinical effects on the central nervous system, including effects on olfactory and some cognitive functions. However, no widespread pattern of cognitive deficits was observed. The peripheral nerve effects were likely caused by ergonomic stresses experienced by the fumigation workers.
本研究评估了结构熏蒸工人职业接触甲基溴和硫酰氟对健康的影响。
对南佛罗里达州的123名结构熏蒸工人和120名对照人员进行了横断面研究。包括神经传导、振动、神经行为、视觉、嗅觉和肾功能测试。
工人中甲基溴和硫酰氟的终生接触时间中位数分别为1.20年和2.85年。检查前一年硫酰氟接触与图案记忆测试和嗅觉测试表现显著降低有关。此外，熏蒸工人优势手的圣安娜灵巧度测试表现显著降低，腕管综合征患病率高于对照人员，但差异不显著。
职业性硫酰氟接触可能与对中枢神经系统的亚临床影响有关，包括对嗅觉和一些认知功能的影响。然而，未观察到广泛的认知缺陷模式。周围神经影响可能是由熏蒸工人经历的人体工程学压力引起的。
