Luttkus A, Friedmann W, Dudenhausen J W
Abt. für Geburtshilfe, Humboldt-Universität Berlin.
Gynakol Geburtshilfliche Rundsch. 1995;35 Suppl 1:122-5.
Does the knowledge of fetal oxygen saturation allow to avoid fetal scalp blood sampling and to predict a pH < or = 7.25 of the fetal blood sample?
Out of a group of 135 fetuses we determined the median, the 10th, 5th and 3rd percentile of oxygen saturation values by a blinded fetal pulse oximeter. Due to abnormal FHR-patterns, 110 fetal scalp blood samples (FBA) were assessed by the technique introduced by Saling. The pH of these FBA's ranged from 7,16-7,48 (median 7,28). We chose a 20 minute period before the FBA and calculated the individual median and percentiles. According to the pH of < or = 7,25 in FBA we calculated the chi-square test for significance.
The median of <35% SpO2 has a sensitivity of 23%, specificity of 77%, positive predictive value of 27% and a negative predictive value of 73%.
Fetal oxygen saturation alone shows a high specificity and a low sensitivity for pH < 7,25. In addition to FHR monitoring, pulse oximetry.
了解胎儿血氧饱和度是否能避免进行胎儿头皮血采样，并预测胎儿血样pH值≤7.25？
在一组135例胎儿中，我们使用盲法胎儿脉搏血氧仪确定了血氧饱和度值的中位数、第10百分位数、第5百分位数和第3百分位数。由于胎心率模式异常，采用萨林介绍的技术对110例胎儿头皮血样本（FBA）进行了评估。这些FBA样本的pH值范围为7.16 - 7.48（中位数7.28）。我们在FBA采样前选择了20分钟的时间段，并计算了个体中位数和百分位数。根据FBA中pH值≤7.25的情况，我们计算了卡方检验的显著性。
SpO2＜35%的中位数敏感性为23%，特异性为77%，阳性预测值为27%，阴性预测值为73%。
仅胎儿血氧饱和度对pH＜7.25显示出高特异性和低敏感性。除胎心率监测外，还有脉搏血氧测定法。
