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由粪类圆线虫播散性感染相关的小叶间隔纤维化所致的限制性肺疾病。

Restrictive pulmonary disease due to interlobular septal fibrosis associated with disseminated infection by Strongyloides stercoralis.

作者信息

Lin A L, Kessimian N, Benditt J O

机构信息

Division of Pulmonary Medicine, Memorial Hospital of Rhode Island, Pawtucket.

出版信息

Am J Respir Crit Care Med. 1995 Jan;151(1):205-9. doi: 10.1164/ajrccm.151.1.7812554.

DOI:10.1164/ajrccm.151.1.7812554
PMID:7812554
Abstract

Strongyloidiasis is caused by the nematode Strongyloides stercoralis. The parasite has a unique life cycle that enables it to cause a hyperinfection syndrome in which pulmonary involvement is characteristic. We describe the case of a 68-yr-old Hispanic male from Puerto Rico with disseminated strongyloidiasis who developed intense granulomatous reaction in the lung associated with interlobular septal fibrosis. Granulomatous lung disease leading to fibrosis within the lung has been well demonstrated in schistosomiasis, another parasitic disease. This case represents the first report, as far as we are aware, of fibrosis within the lung and restrictive pulmonary disease in association with Strongyloides stercoralis.

摘要

类圆线虫病由线虫类圆线虫引起。该寄生虫具有独特的生命周期,使其能够引发一种以肺部受累为特征的超感染综合征。我们描述了一例来自波多黎各的68岁西班牙裔男性播散性类圆线虫病病例,该患者肺部出现了与小叶间隔纤维化相关的强烈肉芽肿反应。在另一种寄生虫病血吸虫病中,已充分证实肉芽肿性肺病可导致肺部纤维化。据我们所知,该病例是首例关于类圆线虫病伴发肺部纤维化和限制性肺病的报告。

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Restrictive pulmonary disease due to interlobular septal fibrosis associated with disseminated infection by Strongyloides stercoralis.由粪类圆线虫播散性感染相关的小叶间隔纤维化所致的限制性肺疾病。
Am J Respir Crit Care Med. 1995 Jan;151(1):205-9. doi: 10.1164/ajrccm.151.1.7812554.
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The Worm that Clogs the Lungs: Strongyloides Hyper-Infection Leading to Fatal Acute Respiratory Distress Syndrome (ARDS).堵塞肺部的蠕虫:类圆线虫超感染导致致命的急性呼吸窘迫综合征(ARDS)
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Pulmonary strongyloidiasis causing septic shock in a patient with Crohn's disease.肺部类圆线虫病在一名克罗恩病患者中引发感染性休克。
Respir Med Case Rep. 2018 Apr 6;24:52-54. doi: 10.1016/j.rmcr.2018.04.003. eCollection 2018.
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Parasitic infestation of lung: An unusual cause of interstitial pneumonitis.肺部寄生虫感染:间质性肺炎的一种罕见病因。
Lung India. 2016 Mar-Apr;33(2):222-4. doi: 10.4103/0970-2113.177456.
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Severe strongyloidiasis: a systematic review of case reports.严重的类圆线虫病:病例报告的系统评价。
BMC Infect Dis. 2013 Feb 8;13:78. doi: 10.1186/1471-2334-13-78.
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Pulmonary Strongyloidiasis: The Varied Clinical Presentations.肺类圆线虫病:多样的临床表现
Clin Pulm Med. 2004 Jan;11(1):6-13. doi: 10.1097/01.cpm.0000107609.50629.69.