伴有肉瘤样变的肝细胞癌：双期增强CT的特征性表现
Hepatocellular carcinoma with sarcomatous change: characteristic findings of two-phased incremental CT.
作者信息
Honda H, Hayashi T, Yoshida K, Takenaka K, Kaneko K, Fukuya T, Tateshi Y, Ro T, Maeda T, Masuda K
机构信息
Department of Radiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
Abdom Imaging. 1996 Jan-Feb;21(1):37-40. doi: 10.1007/s002619900006.
BACKGROUND
Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC.
METHODS
Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed.
RESULTS
All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathological delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes.
CONCLUSIONS
The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.
背景
由于其预后较差，肝细胞癌伴肉瘤样变（HCCSC）的诊断在临床上具有重要意义。本研究的目的是阐明HCCSC的特征性CT表现。
方法
回顾性分析6例经组织学证实的HCCSC的双期动态增强CT图像。
结果
所有肿瘤（100%）在延迟CT图像上均表现为周边强化。100%（6例中的6例）观察到淋巴结肿大；83%（6例中的5例）出现肝内转移。两个转移灶均表现出与原发性肝肿瘤相似的表现，如周边强化。组织病理学上，延迟和/或延长的周边强化区域由具有肉瘤样变的存活癌细胞组成。
结论
HCCSC在CT上的表现为肝内边界不规则的肿块，伴有延迟或延长的周边强化，常伴有肝内转移和淋巴结肿大。
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