Kollerstrom N, Lord P W, Whimster W F
Thorax. 1977 Apr;32(2):160-2. doi: 10.1136/thx.32.2.160.
The percentage area of the bronchial glands taking up the Alcian blue (pH 2-6) stain for acid mucin was obtained from sections from the trachea and from each generation down the inferior lingular axial bronchial pathway in five non-smokers and five cigarette smokers. The mean percentage value for the smokers (59-5%) was significantly less than for the non-smokers (74-4%). The percentage increased between successive generations from the trachea by an average of 6-5. This gradient did not differ significantly between the smoking and non-smoking groups. It was not possible to attribute these differences to any specific mechanism because many interacting variables were involved which could not be measured. Nevertheless the percentage mucin retention or storage provides an introduction to consideration of these variables and their response to cigarette smoke.
从五名不吸烟者和五名吸烟者的气管及下舌叶轴向支气管通路各代分支的切片中，获取支气管腺体摄取阿尔辛蓝（pH 2 - 6）酸性粘蛋白染色的面积百分比。吸烟者的平均百分比值（59.5%）显著低于不吸烟者（74.4%）。从气管开始，各代之间的百分比平均增加6.5%。吸烟组和非吸烟组之间的这一梯度差异不显著。由于涉及许多无法测量的相互作用变量，因此无法将这些差异归因于任何特定机制。然而，粘蛋白保留或储存的百分比为考虑这些变量及其对香烟烟雾的反应提供了一个切入点。
