Rafałowska J, Drac H, Dziewulska D, Bojakowski J
Department of Neurology, School of Medicine, Warszawa.
Folia Neuropathol. 1995;33(4):247-50.
Authors present two cases of basilar artery aneurysm accompanied by different development failures of blood vessels. In both cases anomaly in formation of brain base vessels, angioma consisted of different size thin-walled vessels and arterio-venous angioma within brain stem were stated. Besides, conglomerates of abnormal vessels, angiosis within pia matter, diffused lacunar and fetal as well as thin-walled venous vessels were found. Pathological vessels, their conglomerates were present in brain stem, cerebellum and cerebral hemispheres. The variability of vascular malformations seems to point at long-lasting action pathogenic factor during ontogenesis. Authors try to refer particular developmental anomalies to proper stage of ontogenesis.
作者报告了两例伴有不同血管发育异常的基底动脉动脉瘤病例。在这两例病例中,均发现脑基底血管形成异常,血管瘤由大小各异的薄壁血管组成,且脑干内存在动静脉血管瘤。此外,还发现了异常血管团、软膜内血管增生、弥漫性腔隙及胚胎性薄壁静脉血管。病理性血管及其血管团存在于脑干、小脑和大脑半球。血管畸形的多样性似乎表明在个体发育过程中存在长期作用的致病因素。作者试图将特定的发育异常归因于个体发育的适当阶段。