York M J, Hutton W C
Department of Orthopaedics, Emory University School of Medicine, Atlanta, Ga, USA.
J South Orthop Assoc. 1996 Spring;5(1):5-12.
We surgically applied compression plates, secured with cortical screws, to the anterolateral surface of each radius in 20 dogs. Five weeks later, the plates and screws were removed. The dogs were then divided into four groups of 5, and each group had the screw holes in the left radii filled with a different form of bone graft material. The screw holes in the right radii received no graft material and served as controls. Five weeks later the dogs were euthanized, and the radii were removed and torqued to failure. All bones failed through a previous screw hole. An analysis of variance comparing all grafted radii to the ungrafted controls revealed no significant difference in torque to failure. This suggests that both grafted and ungrafted screw holes still increase stress at 5 weeks, and any period of protection after plate removal should be longer than 5 weeks. However, histology revealed that the holes filled with graft material had, in every case, more bone in the screw holes than did the holes in the ungrafted controls.
我们通过手术将用皮质骨螺钉固定的加压接骨板应用于20只狗的每根桡骨的前外侧表面。五周后，取出接骨板和螺钉。然后将这些狗分成四组，每组5只，每组左桡骨的螺钉孔用不同形式的骨移植材料填充。右桡骨的螺钉孔不植入移植材料，作为对照。五周后对狗实施安乐死，取出桡骨并扭转至断裂。所有骨头均通过先前的螺钉孔断裂。对所有植入移植材料的桡骨与未植入移植材料的对照进行方差分析，结果显示断裂扭矩无显著差异。这表明植入和未植入移植材料的螺钉孔在5周时仍会增加应力，并且取出接骨板后的任何保护期都应超过5周。然而，组织学检查显示，在每种情况下，填充有移植材料的孔中的骨量都比未植入移植材料的对照孔中的骨量多。
