Roland J, van den Weyngaert D, Krug B, Brans B, Scalliet P, Vandevivere J
Department of Nuclear Medicine, Middelheim General Hospital, Antwerp, Belgium.
Clin Nucl Med. 1995 Dec;20(12):1052-4. doi: 10.1097/00003072-199512000-00002.
Although bone scintigraphy is an extremely sensitive method for the detection of focal bone disease, small lesions below the resolution of planar imaging may be missed. This is a report of a patient with carcinoma of the breast who showed tumor progression 1 year after initial treatment. Complete evaluation was performed in order to detect the origin of increased level of a tumor marker. Although planar bone scintigraphy could not demonstrate any lesion in the spine, multiple metastases were detected in the lumbar and the thoracic spines on SPECT imaging. Only some of these lesions were seen with MRI. Repeat planar bone imaging 6 weeks later showed multiple bone lesions in the lumbar and thoracic areas.
尽管骨闪烁显像术是检测局灶性骨病的一种极其敏感的方法，但平面成像分辨率以下的小病灶可能会被漏诊。本文报告一名乳腺癌患者，其在初始治疗1年后出现肿瘤进展。为了检测肿瘤标志物水平升高的来源，进行了全面评估。尽管平面骨闪烁显像术未显示脊柱有任何病灶，但单光子发射计算机断层扫描（SPECT）成像发现腰椎和胸椎有多处转移灶。磁共振成像（MRI）仅显示了其中部分病灶。6周后重复平面骨显像显示腰椎和胸椎区域有多处骨病灶。
