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[妊娠期乳腺癌]

[Breast cancer during pregnancy].

作者信息

Jereczek B

机构信息

Kliniki Onkologii i Radioterapii Akademii Medycznej w Gdańsku.

出版信息

Ginekol Pol. 1995 Aug;66(8):480-3.

PMID:8675075
Abstract

Approximately 2-3% of all breast cancers coincide with pregnancy or lactation and this tumour affects one to four out of 10000 pregnant women. Breast cancer associated with pregnancy (BCAP) has generally been believed to have a particularly grim prognosis. Several recent studies suggest however, that survival in BCAP does not substantially differ from that of non-pregnant, age and stage matched patients. BCAP may managed with standard methods. Surgery should be considered in all patients deemed to be operable. Therapeutic abortion does not need to be routinely performed, unless adjuvant chemotherapy or radiotherapy is to be applied or the patient necessitates systemic therapy for advanced disease. Prophylactic ovarian ablation does not influence significantly the course of BCAP and should be undertaken only in case of progressive or recurrent disease.

摘要

所有乳腺癌中约2%-3%与妊娠或哺乳期同时发生,这种肿瘤影响每10000名孕妇中的1至4人。妊娠相关乳腺癌(BCAP)一般被认为预后特别严峻。然而,最近的几项研究表明,BCAP患者的生存率与非妊娠、年龄和分期匹配的患者并无显著差异。BCAP可用标准方法治疗。所有被认为可手术的患者均应考虑手术。除非要进行辅助化疗或放疗,或者患者因晚期疾病需要全身治疗,否则无需常规进行治疗性流产。预防性卵巢切除对BCAP的病程影响不大,仅在疾病进展或复发时才应进行。

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