[Fractional composition and methylation of liver cell nucleus histones during the early stages of radiation injury].

The radiation injury affects the quantitative ratio of histone fractions. The most pronounced changes in the percentage content towards a decrease are observed for the fractions F2a1 and F2a2 as well as for F2a 12 h and 24 h after irradiation, respectively. An increase by 41.8% is observed in the content of the fractions F2b+F3 12 h after irradiation. The methylation for all histones of the fractions increases considerably 2 h after irradiation, drops 12 h later in the fractions F2a1 and F3 and 24 h later in the fractions F3 and F1 as compared to the normal level.