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[1-¹⁴C-乙酸盐掺入再生大鼠肝脏切片的不皂化脂质中]

[Incorporation of 1-14C-acetate into unsaponifiable lipids of slices of regenerating rat liver].

作者信息

Kuz'menko I V, Fedurov V V

出版信息

Ukr Biokhim Zh. 1977 Mar-Apr;49(2):9-11.

PMID:867541
Abstract

Incorporation of 14C into unsaponifiable lipids, sterols and their presursors, hydrocarbons, isolated from sections of the rat regenerating liver studied after their 6-hour incubation with 1-14C-acetate. Intensity of the label incorporation into unsaponifiable lipids and sterols increases significantly the first three days after hepatectomy and decreases on the 15th day, intensity of incorporation into hydrocarbons rises significantly the first six days and lowers on the 15th days after hepatectomy. The label is observed to be incorporated more intensively into the total unsaponifiable lipids and hydrocarbon fraction as compared to sterols, that may evidence for activation of these compounds biosynthesis at initial stages.

摘要

将大鼠再生肝组织切片与1-¹⁴C-醋酸盐孵育6小时后,从其中分离出的不皂化脂质、固醇及其前体、烃类中¹⁴C的掺入情况。肝切除术后的头三天,不皂化脂质和固醇中标记掺入的强度显著增加,而在第15天降低;烃类中掺入强度在肝切除术后的头六天显著上升,在第15天降低。与固醇相比,标记在总不皂化脂质和烃类部分中的掺入更为强烈,这可能证明这些化合物在初始阶段的生物合成被激活。

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