Herholz H, Goff D C, Ramsey D J, Chan F A, Ortiz C, Labarthe D R, Nichaman M Z
Epidemiology Research Center, The University of Texas, School of Public Health, Houston, Texas 77225, USA.
J Clin Epidemiol. 1996 Mar;49(3):279-87. doi: 10.1016/0895-4356(95)00572-2.
Mortality following myocardial infarction (MI) is greater among women than men and among Mexican Americans than non-Hispanic whites. Because therapy can affect mortality following MI, we examined differences in discharge therapy among these groups. Data regarding discharge therapy of 982 patients in the Corpus Christi Heart Project showed that women received fewer cardiovascular drugs than men, and Mexican Americans received fewer cardiovascular drugs than non-Hispanic whites. In multivariate analysis adjusting for age, cigarettes smoking, diabetes, hypertension, congestive heart failure, and serum cholesterol, the odds ratio for receipt of cardiovascular medications was 0.51 (95% CI: 0.28-0.93) for women versus men and 0.62 (0.3-1.15) for Mexican Americans versus non-Hispanic whites. Beta-blockers were prescribed rarely. Thus, treatment differences between ethnic and gender groups were observed following MI. Further research is needed to determine both the reasons for these differences and the extent to which these differences contribute to the observed survival patterns following MI.
心肌梗死（MI）后的死亡率在女性中高于男性，在墨西哥裔美国人中高于非西班牙裔白人。由于治疗可影响心肌梗死后的死亡率，我们研究了这些群体在出院治疗方面的差异。科珀斯克里斯蒂心脏项目中982例患者的出院治疗数据显示，女性接受的心血管药物比男性少，墨西哥裔美国人接受的心血管药物比非西班牙裔白人少。在对年龄、吸烟、糖尿病、高血压、充血性心力衰竭和血清胆固醇进行校正的多变量分析中，女性与男性相比接受心血管药物治疗的优势比为0.51（95%可信区间：0.28 - 0.93），墨西哥裔美国人与非西班牙裔白人相比为0.62（0.3 - 1.15）。β受体阻滞剂的处方很少。因此，心肌梗死后观察到了不同种族和性别群体之间的治疗差异。需要进一步研究以确定这些差异的原因以及这些差异在多大程度上导致了心肌梗死后观察到的生存模式。
