Ghayad E, Tohme A
Section of Internal Medicine, Hôtel-Dieu de France Hospital of Beirut, Lebanon.
J Med Liban. 1995;43(1):2-7.
To present clinical features of Behçet's disease in Lebanon and to evaluate the efficacy of treatment.
The 100 patients are seen at Hotel-Dieu de France Hospital of Beirut between 1980 and 1992. Diagnostic criteria are those of the Behçet Syndrome Research Committee of Japan.
Recurrent oral ulcers are present in 95% of cases, genital ulcers in 78%, ocular manifestations are more frequent than those of several studies whereas skin lesions and vascular signs are less frequent. Joint involvement are recorded in 65% of cases and neurological one in 14%. The effectiveness of colchicine therapy is confirmed for mucocutaneous lesions and arthritis. Immunosuppressive agents are more beneficial than steroids alone on serious uveitis. An aggressive treatment with corticosteroids and immunosuppressive drugs improve the prognosis of meningoencephalitis.
Behçet's disease doesn't have any specific characteristics in Lebanon despite some variation in the frequency of lesions.
介绍黎巴嫩白塞病的临床特征并评估治疗效果。
1980年至1992年间在贝鲁特法国主宫医院就诊的100例患者。诊断标准采用日本白塞综合征研究委员会的标准。
95%的病例有复发性口腔溃疡，78%有生殖器溃疡，眼部表现比多项研究中的更为常见，而皮肤病变和血管体征则较少见。65%的病例有关节受累，14%有神经受累。秋水仙碱治疗对黏膜皮肤病变和关节炎的有效性得到证实。在严重葡萄膜炎方面，免疫抑制剂比单独使用类固醇更有益。积极使用皮质类固醇和免疫抑制药物可改善脑膜脑炎的预后。
尽管病变频率存在一些差异，但黎巴嫩的白塞病没有任何特定特征。
