Nakazato Y, Nakata Y, Yasuda M, Yamagami S, Tokano T, Nakazato K, Sumiyoshi M, Ogura S, Yamaguchi H
Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Jpn Heart J. 1996 Mar;37(2):265-9. doi: 10.1536/ihj.37.265.
We report the case of a 38-year-old man who had idiopathic ventricular fibrillation (VF) which initiated by abnormally short-coupled ventricular premature beats. VF was successfully prevented by the combination of pilsicainide, propranolol, and verapamil. In particular, the effects of pilsicainide are assumed to exert an important effect in controlling this arrhythmia. Class Ic drugs may be effective for preventing VF initiated by short-coupled VPBs.