Pesce G, Acampa G, Pontecorvo C
Università degli Studi, Napoli, IV Divisione di Chirurgia Generale.
Minerva Chir. 1996 Jan-Feb;51(1-2):39-46.
The authors report their experience of the endoscopic removal of 350 polyps of the colon. Vegetating lesions of doubtful endoscopic appearance and nature were excluded from this study. Indications regarding intestinal cleaning and the most appropriate pharmacological preparation are given on the basis of personal experience. No patient had to be hospitalised and the colon was fully explored in all cases; the cecum was reached in 85% of cases. The maximum limit of endoscopic removal was 5 cm due to the greater risk of complications and presence of cancer on polyps. A total of up to 8 polyps were removed in a single session in cases of multiple polyposis. From 1986 to 1992 350 polypectomies were performed in 177 patients, of which 301 were adenoma (85.9%) and 49 mixed (14.1%). Adenomas were 80.5% tubular, 13.6% tubulo-villous and 4.3% villous. Cancer was found on polyps in 5 cases (1.6%). 146 polyps were found in the rectum (41.8%), 84 in the sigma (24%), 76 in the descending (21.7%), 21 in the transverse (6%), and 23 in the right colon (6.5%). Patients were aged between 3 and 81 years, and the most frequently affected age bracket was between 40-70 years. Follow-up consisted in checks at 6, 12 and 24 months in cases of adenoma and quarterly checks during the first year in the event of carcinoma in situ. The decision to use a diathermic loop or hot biopsy was made in relation to lesion size, reserving the former for polyps with diameters of over 8 mm. All polyps under 5 cm were removed and subjected to histological tests. No cases of early or late complications were reported in the 350 polypectomies performed. The authors indicate the criteria of choice which led to surgical resection of the first instance. In the event of in situ carcinoma, endoscopic removal is considered sufficient provided that it is radical. The following must be evaluated in the case of invasive carcinoma: tumor size, the degree of differentiation, lymphatic or vascular invasion and generic or specific risk factors linked to the individual patient.
作者报告了他们经内镜切除350例结肠息肉的经验。本研究排除了内镜外观和性质可疑的赘生性病变。根据个人经验给出了肠道清洁及最合适药物准备的指征。所有患者均无需住院,所有病例均对结肠进行了全面探查;85%的病例到达了盲肠。由于息肉出现并发症及癌变的风险更高,内镜切除的最大直径限制为5 cm。在多发性息肉病的病例中,单次手术最多可切除8枚息肉。1986年至1992年,对177例患者实施了350例息肉切除术,其中301例为腺瘤(85.9%),49例为混合型(14.1%)。腺瘤中管状腺瘤占80.5%,管状绒毛状腺瘤占13.6%,绒毛状腺瘤占4.3%。息肉中发现癌变5例(1.6%)。直肠发现146枚息肉(41.8%),乙状结肠84枚(24%),降结肠76枚(21.7%),横结肠21枚(6%),右半结肠23枚(6.5%)。患者年龄在3岁至81岁之间,最常受累的年龄组为40 - 70岁。对于腺瘤患者,随访包括在6个月、12个月和24个月时进行检查;对于原位癌患者,在第一年每季度进行检查。根据病变大小决定使用圈套器或热活检钳,直径超过8 mm的息肉使用圈套器。所有直径小于5 cm的息肉均被切除并进行组织学检查。在实施的350例息肉切除术中,未报告早期或晚期并发症病例。作者指出了导致一审手术切除的选择标准。对于原位癌,只要切除彻底,内镜切除被认为是足够的。对于浸润性癌,必须评估以下因素:肿瘤大小、分化程度、淋巴或血管侵犯以及与个体患者相关的一般或特定风险因素。