Nesbitt T H, Kay H H, McCoy M C, Herbert W N
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Obstet Gynecol. 1996 May;87(5 Pt 2):806-9.
The transient but substantial alterations in the biliary system during pregnancy increase the risk of cholecystitis, choledocholithiasis, and pancreatitis. Traditionally, these disorders are managed conservatively or with operative cholecystectomy. Recent advances in fiber-optic technology allow endoscopy to be used as a safe, effective, and definitive treatment alternative for pancreaticobiliary disease in pregnancy.
Three gravid women with cholelithiasis, acute cholecystitis, and/or gallstone pancreatitis were treated endoscopically with stone extraction and experienced rapid resolution of symptoms and successful pregnancy outcomes.
Aggressive endoscopic intervention for biliary disorders in pregnancy appears to decrease morbidity, mortality, and costs. Endoscopy offers a safer, more effective treatment alternative to prolonged medical management and traditional surgical intervention during pregnancy. Because biliary abnormalities resolve rapidly in the postpartum period, it is unlikely these women will need subsequent treatment.
孕期胆道系统短暂但显著的改变会增加胆囊炎、胆总管结石和胰腺炎的风险。传统上,这些疾病采用保守治疗或手术胆囊切除术。光纤技术的最新进展使内镜检查能够作为孕期胰胆疾病的一种安全、有效且确定性的治疗选择。
三名患有胆结石、急性胆囊炎和/或胆石性胰腺炎的孕妇接受了内镜下取石治疗,症状迅速缓解,妊娠结局成功。
对孕期胆道疾病进行积极的内镜干预似乎可降低发病率、死亡率和成本。与孕期延长的药物治疗和传统手术干预相比,内镜检查提供了一种更安全、更有效的治疗选择。由于产后胆道异常迅速缓解,这些女性不太可能需要后续治疗。