Block P, Kelly T R
Department of Surgery, Akron City Hospital, Northeastern Ohio Universities College of Medicine 44309.
Surg Gynecol Obstet. 1989 May;168(5):426-8.
In a 22 year study, 21 women had acute pancreatitis develop during pregnancy (11 women) or within six weeks post partum (ten women). Gallstones were the cause of the pancreatitis in all. Operation during the acute attack of pancreatitis was required in only two. Acute pancreatitis subsided in the remaining 19 patients; they were operated upon during the second trimester or the early postpartum period. During pregnancy, surgical treatment for gallstone pancreatitis should consist of cholecystectomy and exploration of the common bile duct without operative cholangiography. During the postpartum period, operative cholangiography is used to determine whether or not exploration of the common bile duct is necessary. Acute pancreatitis associated with pregnancy is "gallstone" pancreatitis; there is no evidence that pregnancy is a specific etiologic factor in pancreatitis. As opposed to nonoperative treatment of symptomatic gallstone pancreatitis in pregnancy, which is accompanied by maternal morbidity or fetal mortality, surgical treatment during the optimal time of the second trimester or early postpartum period was associated with no maternal morbidity or fetal mortality and no recurrent pancreatitis.
在一项为期22年的研究中,21名女性在孕期(11名女性)或产后六周内(10名女性)患上了急性胰腺炎。所有病例中胰腺炎的病因均为胆结石。仅2例在胰腺炎急性发作期需要进行手术。其余19例患者的急性胰腺炎症状消退,她们在孕中期或产后早期接受了手术。孕期胆结石性胰腺炎的手术治疗应包括胆囊切除术和胆总管探查,无需术中胆管造影。产后阶段,则使用术中胆管造影来确定是否有必要进行胆总管探查。与妊娠相关的急性胰腺炎是“胆结石性”胰腺炎;没有证据表明妊娠是胰腺炎的特定病因。与孕期有症状的胆结石性胰腺炎的非手术治疗会伴有母体发病或胎儿死亡不同,在孕中期或产后早期的最佳时机进行手术治疗,既不会导致母体发病或胎儿死亡,也不会出现复发性胰腺炎。