Nozdrachev A D
Usp Fiziol Nauk. 1996 Apr-Jun;27(2):28-60.
The article reviews the information available at present on the chemical mediators transmitting excitation in each link of the autonomous reflex are: sensory, inserted and effector. It describes the modern views on the functional structure of these links. On the basis of microelectrode analysis, histochemistry and, in particular, of immunochemistry, detailed analysis is provided of the new concepts of the mediators of the interneuronal and autonomous neuroeffector transmission by classical transmitters, and by the peptide component including P substance, calcitonin-gene-related peptide, VIP, DIN, ANK, etc. Neuropeptide get the key role information of the functional specificity of neurons. Peptides may be secreted and stored together with various neuromediators in presynaptic structures of various links of the reflex are. Special attention is given to the para-, prevertebral and intramural ganglia, which are interpreted as the lowest centres of autonomous periphery having significant integrative abilities. The immunohistochemical studies are reliably indicating that the main ganglionic neurons, the same as the nerve fibres entering the nodes are chemically coded in relation to contents of the transmitting molecules.
本文综述了目前关于自主反射弧各环节（感觉、中间和效应环节）中传递兴奋的化学介质的现有信息。它描述了关于这些环节功能结构的现代观点。基于微电极分析、组织化学，尤其是免疫化学，详细分析了经典递质以及包括P物质、降钙素基因相关肽、血管活性肠肽、生长抑素、神经激肽等肽类成分在中间神经元和自主神经效应器传递介质方面的新概念。神经肽在神经元功能特异性信息方面起着关键作用。肽类可能与各种神经介质一起分泌并储存在反射弧各环节的突触前结构中。特别关注椎旁、椎前和壁内神经节，它们被解释为具有重要整合能力的自主神经外周的最低中枢。免疫组织化学研究可靠地表明，主要的神经节神经元以及进入神经节的神经纤维在传递分子含量方面存在化学编码。
