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小鼠出生后个体发育过程中交感干星状神经节内神经元的免疫细胞化学特征

Immunocytochemical characteristics of neurons in the stellate ganglion of the sympathetic trunk in mice during postnatal ontogenesis.

作者信息

Maslyukov P M, Shilkin V V, Timmermans J-P

机构信息

Department of Normal Physiology and Biophysics and Department of Human Anatomy, Yaroslavl State Medical Academy, Russia.

出版信息

Neurosci Behav Physiol. 2006 Oct;36(8):851-5. doi: 10.1007/s11055-006-0097-6.

DOI:10.1007/s11055-006-0097-6
PMID:16964463
Abstract

The neurotransmitter composition of neurons in the stellate ganglion of mice of different ages (neonatal and aged 10, 20, 30, and 60 days) was studied using an immunocytochemical method. Most of the neurons in the mice of these age groups contained tyrosine hydroxylase (TH). Most choline acetyltransferase (CAT)-positive neurons in neonatal and 10-day mice were also TH-positive. From birth and at all subsequent ages, there were increases in the proportion of cells contained TH and neuropeptide Y. The proportion of neurons containing vasoactive intestinal peptide and CAT increased to 10 days of life and then decreased. Somatostatin-and galanin-positive neurons were absent from all animals. Maturation of the set of neurotransmitters in stellate ganglia was complete by age two months.

摘要

采用免疫细胞化学方法研究了不同年龄(新生及10、20、30和60日龄老龄)小鼠星状神经节中神经元的神经递质组成。这些年龄组小鼠的大多数神经元含有酪氨酸羟化酶(TH)。新生和10日龄小鼠中大多数胆碱乙酰转移酶(CAT)阳性神经元也是TH阳性。从出生及随后所有年龄段,含有TH和神经肽Y的细胞比例均增加。含有血管活性肠肽和CAT的神经元比例在出生后10天增加,然后下降。所有动物均未发现生长抑素和甘丙肽阳性神经元。星状神经节中神经递质组的成熟在两个月龄时完成。

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Histochemical features of neurons in the cat stellate ganglion during postnatal ontogenesis.
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