Kawano S, Terada K, Hiraga Y, Morita T
Department of Pediatrics, Kawasaki Medical School, Okayama, Japan.
Acta Paediatr Jpn. 1996 Apr;38(2):121-3. doi: 10.1111/j.1442-200x.1996.tb03452.x.
Specific cellular immunity against the whole antigen and glycoprotein I (gp I) of varicella-zoster virus (VZV) and the skin test antigen were determined for 13 healthy immune adults to compare the immunogenicity of these antigens using a lymphoproliferative assay. The stimulation index values (mean +/- s.d.) were 16.4 +/- 11.2 against the whole VZV antigen, 4.2 +/- 2.9 against the VZV skin test antigen and 1.1 +/- 0.5 against gp I. The immunogenicity of the skin test antigen, which mainly contains gp III and gp IV, appears to be more favorable than that of gp I alone, but to be weaker than that of the whole VZV antigen.
采用淋巴细胞增殖试验，对13名健康免疫成人测定了针对水痘 - 带状疱疹病毒（VZV）全抗原、糖蛋白I（gp I）以及皮肤试验抗原的特异性细胞免疫，以比较这些抗原的免疫原性。针对VZV全抗原的刺激指数值（均值±标准差）为16.4±11.2，针对VZV皮肤试验抗原的刺激指数值为4.2±2.9，针对gp I的刺激指数值为1.1±0.5。主要包含gp III和gp IV的皮肤试验抗原的免疫原性似乎比单独的gp I更优，但比VZV全抗原的免疫原性弱。
