Sandlund J T, Miser J S, Miser A W
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
Am J Clin Oncol. 1996 Aug;19(4):349-50. doi: 10.1097/00000421-199608000-00005.
Neutrophilic dermatosis (Sweet syndrome) is a rare condition characterized by painful indurated cutaneous plaques infiltrated with mature neutrophils and may be accompanied by fever, granulocytosis, arthritis, and conjunctivitis. It is associated with various malignant and preneoplastic states, the most common being leukemia and myeloproliferative disorders. Its association with solid tumors is infrequent. The case described here represents, to our knowledge, the first report of Sweet syndrome in a patient with osteogenic sarcoma, a primary tumor of bone arising from mesenchymal cells.
中性粒细胞性皮肤病（Sweet综合征）是一种罕见疾病，其特征为疼痛性硬结性皮肤斑块，有成熟中性粒细胞浸润，可能伴有发热、粒细胞增多、关节炎和结膜炎。它与多种恶性和癌前状态相关，最常见的是白血病和骨髓增殖性疾病。它与实体瘤的关联并不常见。据我们所知，此处描述的病例是成骨肉瘤（一种起源于间充质细胞的原发性骨肿瘤）患者中Sweet综合征的首例报告。
