Miller M, Crippin J S, Klintmalm G
Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas, USA.
Am J Gastroenterol. 1996 Jul;91(7):1427-9.
Hepatic parenchymal iron deposition is a well-known complication of chronic hepatic inflammatory states. This can make the differential between chronic hepatitis and hereditary hemochromatosis difficult, however. The case of a 13-yr-old male with chronic hepatitis C and hereditary hemochromatosis resulting in end stage liver disease and the need for orthotopic liver transplantation is described. There has been no previously described case of the coexistence of these two diseases in a pediatric patient, resulting in end stage liver disease. The progression to cirrhosis in a patient of this age suggests a more rapid progression of the combined diseases than with either disease alone.
肝实质铁沉积是慢性肝脏炎症状态的一种众所周知的并发症。然而，这可能会使慢性肝炎和遗传性血色素沉着症之间的鉴别变得困难。本文描述了一名13岁男性患者的病例，该患者患有慢性丙型肝炎和遗传性血色素沉着症，导致终末期肝病并需要进行原位肝移植。此前尚无关于这两种疾病在儿科患者中共存并导致终末期肝病的病例报道。该年龄患者进展为肝硬化表明，与单一疾病相比，这两种疾病合并存在时进展更为迅速。
