Ross P D
Hawaii Osteoporosis Center, Honolulu.
Arch Intern Med. 1996 Jul 8;156(13):1399-411. doi: 10.1001/archinte.156.13.1399.
More than half of all women and about one third of men will experience osteoporotic fractures during their lives. Although no symptoms occur prior to fracture, bone mineral density and other risk factors can be used to identify high-risk patients, and because effective interventions exist, many of these fractures are now preventable. The proportion of people who are affected, the mortality and morbidity resulting from osteoporotic fractures, and the major known risk factors are discussed. Greater attention should be given to measuring bone mineral density and identifying other risk factors to quantitate the degree of fracture risk among patients (with or without a history of previous fractures), because the consequences of fractures often are severe, and no symptoms other than fractures are associated with disease progression.
超过半数的女性和大约三分之一的男性在一生中会发生骨质疏松性骨折。虽然骨折前没有症状，但骨密度和其他风险因素可用于识别高危患者，并且由于存在有效的干预措施，现在许多此类骨折是可以预防的。本文讨论了受影响人群的比例、骨质疏松性骨折导致的死亡率和发病率以及主要的已知风险因素。应更加重视测量骨密度和识别其他风险因素，以量化患者（无论有无既往骨折史）的骨折风险程度，因为骨折的后果往往很严重，而且除了骨折外没有其他症状与疾病进展相关。
