源自禽逆转录病毒株诱导的大鼠肉瘤的新建立细胞系的V-SRC表达及染色体分析
Expression of V-SRC and chromosome analysis of a newly established cell line from rat sarcoma induced by an avian retroviral strain.
作者信息
Polianova M T, Jordanova P K
机构信息
National Center of Infectious and Parasitic Diseases, Central AIDS Laboratory, Bulgarian Academy of Sciences, Sofia, Bulgaria.
出版信息
Arch Virol. 1996;141(5):801-8. doi: 10.1007/BF01718156.
PMID:8678827
Abstract
In the newly established rat sarcoma cell line LSR-SF (SR) expression of pp60v-src was detected. Karyotype analyses revealed various chromosome aberrations during prolonged passaging of the tumor cells in vitro. Polyploidy was found to be a characteristic feature of the line studied. A large metacentric chromosome persistently present in the cells was accepted as a line marker.
摘要
在新建立的大鼠肉瘤细胞系LSR-SF（SR）中检测到了pp60v-src的表达。核型分析显示，肿瘤细胞在体外长期传代过程中出现了各种染色体畸变。多倍体被发现是所研究细胞系的一个特征性特点。细胞中持续存在的一条大的中着丝粒染色体被用作细胞系标记。
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