大鼠Pgy3（mdr2）定位于4q11 - 12上与Pgy2（mdr1b）相同的区域。 - Suppr

Localization of rat Pgy3 (mdr2) to the same region as Pgy2 (mdr1b) at 4q11-12.

作者信息

Zimonjic D B, Popescu N C, Brown P C, Silverman J A

机构信息

Laboratory of Biology, National Cancer Institute, Bethesda, Maryland 20892, USA.

出版信息

Mamm Genome. 1996 Aug;7(8):630-1. doi: 10.1007/s003359900295.

DOI:10.1007/s003359900295

PMID:8679007

Abstract

摘要

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Localization of rat Pgy3 (mdr2) to the same region as Pgy2 (mdr1b) at 4q11-12.

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Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.

Cell. 1993 Nov 5;75(3):451-62. doi: 10.1016/0092-8674(93)90380-9.

Cloning and regulation of the rat mdr2 gene.

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Phosphatidylcholine translocase: a physiological role for the mdr2 gene.

Cell. 1994 Jul 1;77(7):1071-81. doi: 10.1016/0092-8674(94)90446-4.

Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.

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Localization of the multidrug resistance-associated 170 kDa P-glycoprotein gene to mouse chromosome 5 and to homogeneously staining regions in multidrug-resistant mouse cells by in situ hybridization.

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Structure of the human MDR3 gene and physical mapping of the human MDR locus.

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Localization of rat Pgy3 (mdr2) to the same region as Pgy2 (mdr1b) at 4q11-12.

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Localization of rat Pgy3 (mdr2) to the same region as Pgy2 (mdr1b) at 4q11-12.

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